Founded as Droplet Genomics in 2016, Atrandi grew from years spent at the intersection of engineering and biology – close enough to the limits of existing tools to understand exactly where they failed. Running multi-step workflows within droplets meant constant compromises between compatibility, control, and performance. Semi-Permeable Capsule technology was developed to solve that specific problem. By isolating single cells while allowing reagents to move freely, SPCs made it possible to run complex multi-step workflows under optimal conditions – something no existing system could do. What began as a technical solution became a new way to think about single-cell analysis entirely.