ResolveDNA Whole Genome Amplification Kits overcome the inherent challenges of low coverage uniformity in single-cell genomics that lead to increased sequencing costs and complex data analysis.

The controlled reaction parameters employed in this PTA-based kit enables reproducible recovery of >95% of the genomes of single cells and limited DNA input samples with industry-leading uniformity and accuracy.

Key features and benefits of ResolveDNA Whole Genome Amplification Kits include:

– Complete genomic coverage with bulk sample quality from a single cell
– Significantly lower allelic dropout and biases compared to existing WGA methods that yield low and variable coverage across the genome
– Specific amplification of the primary template with >97% of reads mapping to the human genome
– Low-cost, scalable approach to WGA with up to 384 reactions per kit
– Simple, user-friendly workflow that can be set up with automation
– Protocols available to create libraries for whole genome sequencing (WGS) or hybridization capture for whole exome or targeted panel sequencing

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